Evidence for Microbial Biofilms in Cholesteatomas

Evidence for microbial biofilms in cholesteatomas.

BACKGROUND Sessile bacteria within biofilms are highly resistant to eradication by antimicrobial agents. Previously, we have shown that the most common organisms cultured from experimentally induced cholesteatomas are biofilm formers. Additionally, the keratin "matrix" of a cholesteatoma is an ideal environment for the support of biofilm formation. OBJECTIVE To determine if microbial biofilms...

Microbial Biofilms

Gene transfer in microbial biofilms

Quantification and prediction of gene transfer in natural environments is required for reliable assessment of risks associated with the transfer of recombinant DNA in genetically engineered microbial inocula, and for a greater understanding of the mechanisms controlling transfer of genetic material. Published models of gene transfer describe plasmid transfer in homogeneous, liquid culture syste...

Microbial Biofilms, Second Edition

M Biofilms provides an overview of the formation, structure/architecture, cell-to-cell interactions, and dispersal of fungal and bacterial biofilms. The target audience is biofilm researchers, but this second edition of the book should also be useful for healthcare practitioners seeking a better understanding of microbial biofilms in healthcare delivery. The number of published papers pertainin...

Mathematical Description of Microbial Biofilms

We describe microbial communities denoted biofilms and efforts to model some of their important aspects, including quorum sensing, growth, mechanics, and antimicrobial tolerance mechanisms.